Version 5.4
| Mus musculus Gene: Fastk | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-141355.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Fastk | ||||||||
| Gene Name | Fas-activated serine/threonine kinase | ||||||||
| Synonyms | 0610011K02Rik; 610011K02Rik | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000028959 | ||||||||
| Encoded Proteins |
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164896:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 5:24438440-24445287 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A3 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | D3Z4M5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 66587 | ||||||||
| UniGene | Mm.28123 Mm.481428 | ||||||||
| RefSeq | NM_023229 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS19120 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1913837 | ||||||||
| MGI Symbol | Fastk | ||||||||
| EMBL | AC120353 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 66587 | ||||||||