Mus musculus Gene: Fastk | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-141355.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Fastk | ||||||||
Gene Name | Fas-activated serine/threonine kinase | ||||||||
Synonyms | 0610011K02Rik; 610011K02Rik | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000028959 | ||||||||
Encoded Proteins |
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
Fas-activated serine/threonine kinase
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164896:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 5:24438440-24445287 | ||||||||
Strand | Reverse strand | ||||||||
Band | A3 | ||||||||
Transcripts | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | D3Z4M5 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 66587 | ||||||||
UniGene | Mm.28123 Mm.481428 | ||||||||
RefSeq | NM_023229 | ||||||||
OMIM | |||||||||
CCDS | CCDS19120 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | MGI:1913837 | ||||||||
MGI Symbol | Fastk | ||||||||
EMBL | AC120353 | ||||||||
GenPept | |||||||||
RNA Seq Atlas | 66587 | ||||||||