Version 5.4
Homo sapiens Gene: NUBP1
Summary
InnateDB Gene IDBG-14313.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUBP1
Gene Name nucleotide binding protein 1
Synonyms NBP; NBP1; NBP35
Species Homo sapiens
Ensembl Gene ENSG00000103274
Encoded Proteins
IDBP-14315
nucleotide binding protein 1
IDBP-368432
nucleotide binding protein 1
IDBP-746087
IDBP-747980
IDBP-748201
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:10743786-10769351
Strand Forward strand
Band p13.13
Transcripts
ENST00000283027 ENSP00000283027
ENST00000433392 ENSP00000409654
ENST00000571790
ENST00000574691 ENSP00000461723
ENST00000574334 ENSP00000461746
ENST00000571175 ENSP00000460288
ENST00000574137
ENST00000573663
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 19 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006879 cellular iron ion homeostasis
GO:0010826 negative regulation of centrosome duplication
GO:0016049 cell growth
GO:0016226 iron-sulfur cluster assembly
GO:0044281 small molecule metabolic process
GO:0051642 centrosome localization
GO:0072697 protein localization to cell cortex
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022503
View Gene Order
ENSBTAG00000009560
Not yet available
Pathways
NETPATH
REACTOME
REACT_160176
Cytosolic iron-sulfur cluster assembly pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 4682
UniGene Hs.81469
RefSeq NM_001278506 NM_002484
HUGO HGNC:8041
OMIM 600280
CCDS CCDS10543 CCDS61839
HPRD 02611
IMGT
EMBL
GenPept
RNA Seq Atlas 4682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca