Version 5.4
Mus musculus Gene: Tcerg1
Summary
InnateDB Gene IDBG-143299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tcerg1
Gene Name transcription elongation regulator 1 (CA150)
Synonyms 2410022J09Rik; 2900090C16Rik; AI428505; ca150; CA150b; FBP23; FBP28; p144; Taf2s
Species Mus musculus
Ensembl Gene ENSMUSG00000024498
Encoded Proteins
IDBP-143301
transcription elongation regulator 1 (CA150)
IDBP-622444
transcription elongation regulator 1 (CA150)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113649:
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:42511510-42575551
Strand Forward strand
Band B3
Transcripts
ENSMUST00000025375 ENSMUSP00000025375
ENSMUST00000173642 ENSMUSP00000134458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0070064 proline-rich region binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113649
View Gene Order
ENSBTAG00000003259
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt Q8CGF7
TrEMBL Q3TH57 Q61050
UniProt Splice Variant
Entrez Gene 56070
UniGene Mm.270511
RefSeq NM_001039474 XM_006526112
OMIM
CCDS CCDS29214
HPRD
IMGT
MGI ID MGI:1926421
MGI Symbol Tcerg1
EMBL AB023485 AK082750 AK168434 BC039185 BC040284 CH466528 U40748 U40749
GenPept AAC52476 AAC52477 AAH39185 AAH40284 BAA86392 BAC38600 BAE40341 EDL10029
RNA Seq Atlas 56070

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca