Version 5.4
Homo sapiens Gene: TCERG1
Summary
InnateDB Gene IDBG-52069.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCERG1
Gene Name transcription elongation regulator 1
Synonyms CA150; TAF2S; Urn1
Species Homo sapiens
Ensembl Gene ENSG00000113649
Encoded Proteins
IDBP-52071
transcription elongation regulator 1
IDBP-241612
transcription elongation regulator 1
IDBP-584968
transcription elongation regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:146447311-146511961
Strand Forward strand
Band q32
Transcripts
ENST00000296702 ENSP00000296702
ENST00000394421 ENSP00000377943
ENST00000507175
ENST00000513298
ENST00000510724
ENST00000509810
ENST00000515203
ENST00000506524
ENST00000505285
ENST00000504116
ENST00000509787
ENST00000514567
ENST00000514719
ENST00000503741
ENST00000511077
ENST00000549332 ENSP00000450414
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 101 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 101 [view]
Protein-Protein 97 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0070064 proline-rich region binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024498
View Gene Order
ENSBTAG00000003259
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3V220
UniProt Splice Variant
Entrez Gene 10915
UniGene Hs.443465 Hs.734605 Hs.735127
RefSeq NM_001040006 NM_006706
HUGO HGNC:15630
OMIM 605409
CCDS CCDS4282 CCDS43379
HPRD 10393
IMGT
EMBL AC011375 CH471062
GenPept EAW61842
RNA Seq Atlas 10915

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca