Version 5.4
Mus musculus Gene: Thoc5
Summary
InnateDB Gene IDBG-143486.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thoc5
Gene Name THO complex 5
Synonyms 1700060C24Rik; A430085L24Rik; Fmip; PK1.3; Sgk2
Species Mus musculus
Ensembl Gene ENSMUSG00000034274
Encoded Proteins
IDBP-143488
THO complex 5
IDBP-143490
THO complex 5
IDBP-537013
THO complex 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100296:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:4895320-4928867
Strand Forward strand
Band A1
Transcripts
ENSMUST00000038237 ENSMUSP00000045580
ENSMUST00000101615 ENSMUSP00000099137
ENSMUST00000142543 ENSMUSP00000118940
ENSMUST00000148117
ENSMUST00000144371
ENSMUST00000155872
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0001824 blastocyst development
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0010468 regulation of gene expression
GO:0010793 regulation of mRNA export from nucleus
GO:0017145 stem cell division
GO:0030224 monocyte differentiation
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0045650 negative regulation of macrophage differentiation
GO:0046784 intronless viral mRNA export from host nucleus
GO:0060215 primitive hemopoiesis
GO:2000002 negative regulation of DNA damage checkpoint
GO:2000035 regulation of stem cell division
Cellular Component
GO:0000346 transcription export complex
GO:0000347 THO complex
GO:0000445 THO complex part of transcription export complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100296
View Gene Order
ENSBTAG00000013150
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q5SVF9
UniProt Splice Variant
Entrez Gene 107829
UniGene Mm.28969
RefSeq NM_172438 XM_006514449
OMIM
CCDS CCDS24393
HPRD
IMGT
MGI ID MGI:1351333
MGI Symbol Thoc5
EMBL AL645522
GenPept
RNA Seq Atlas 107829

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca