Version 5.4
Mus musculus Gene: Tacc1
Summary
InnateDB Gene IDBG-143588.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tacc1
Gene Name transforming, acidic coiled-coil containing protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000065954
Encoded Proteins
IDBP-143590
transforming, acidic coiled-coil containing protein 1
IDBP-143592
transforming, acidic coiled-coil containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147526:
This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:25154552-25201449
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000084030 ENSMUSP00000081043
ENSMUST00000084512 ENSMUSP00000081560
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0022027 interkinetic nuclear migration
GO:0032886 regulation of microtubule-based process
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0015630 microtubule cytoskeleton
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147526
View Gene Order
ENSBTAG00000004238
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
aurora_b_pathway
Aurora B signaling
Cross-References
SwissProt
TrEMBL F8VQ95
UniProt Splice Variant
Entrez Gene 320165
UniGene Mm.308452 Mm.394087 Mm.409527 Mm.456969
RefSeq NM_177089 XM_006509147 NM_199323 XM_006509145 XM_006509146
OMIM
CCDS CCDS40303 CCDS40302
HPRD
IMGT
MGI ID MGI:2443510
MGI Symbol Tacc1
EMBL AC114589
GenPept
RNA Seq Atlas 320165

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca