Mus musculus Gene: Ap1b1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-143791.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Ap1b1 | ||||||||||||||||||||||
Gene Name | adaptor protein complex AP-1, beta 1 subunit | ||||||||||||||||||||||
Synonyms | Adtb1; b2b1660Clo | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000009090 | ||||||||||||||||||||||
Encoded Proteins |
adaptor protein complex AP-1, beta 1 subunit
adaptor protein complex AP-1, beta 1 subunit
adaptor protein complex AP-1, beta 1 subunit
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100280:
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 11:4986824-5042791 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | A1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Membrane Trafficking pathway
Lysosome Vesicle Biogenesis pathway
Immune System pathway
Golgi Associated Vesicle Biogenesis pathway
MHC class II antigen presentation pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Adaptive Immune System pathway
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KEGG |
Lysosome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
MHC class II antigen presentation pathway
Nef mediated downregulation of MHC class I complex cell surface expression pathway
Lysosome Vesicle Biogenesis pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
Adaptive Immune System pathway
Immune System pathway
HIV Infection pathway
The role of Nef in HIV-1 replication and disease pathogenesis pathway
Host Interactions of HIV factors pathway
Disease pathway
Membrane Trafficking pathway
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KEGG |
Lysosome pathway
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INOH | |||||||||||||||||||||||
PID NCI |
Validated nuclear estrogen receptor alpha network
FOXA1 transcription factor network
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | Q5SVG5 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 11764 | ||||||||||||||||||||||
UniGene | Mm.274816 Mm.397718 Mm.487272 | ||||||||||||||||||||||
RefSeq | NM_001243043 NM_001243044 NM_007454 XM_006514461 XM_006514462 XM_006514463 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS36100 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1096368 | ||||||||||||||||||||||
MGI Symbol | Ap1b1 | ||||||||||||||||||||||
EMBL | AL645522 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 11764 | ||||||||||||||||||||||