Mus musculus Gene: Col10a1
Summary
InnateDB Gene IDBG-143867.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Col10a1
Gene Name collagen, type X, alpha 1
Synonyms Col10; Col10a-1;
Species Mus musculus
Ensembl Gene ENSMUSG00000039462
Encoded Proteins
collagen, type X, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123500:
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:34389981-34397085
Strand Forward strand
Band B1
Transcripts
ENSMUST00000105511 ENSMUSP00000101150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001958 endochondral ossification
GO:0051216 cartilage development
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005581 collagen trimer
GO:0005938 cell cortex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Collagen formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
Non-integrin membrane-ECM interactions pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
KEGG
INOH
Integrin signaling pathway pathway
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Collagen biosynthesis and modifying enzymes pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Integrin cell surface interactions pathway
Non-integrin membrane-ECM interactions pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen degradation pathway
Collagen formation pathway
KEGG
INOH
Integrin signaling pathway pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q05306
TrEMBL
UniProt Splice Variant
Entrez Gene 12813
UniGene Mm.443177
RefSeq NM_009925
OMIM
CCDS CCDS23780
HPRD
IMGT
MGI ID MGI:88445
MGI Symbol Col10a1
EMBL X63013 X65121 X67348 Z21610
GenPept CAA44741 CAA46237 CAA47763 CAA79736
RNA Seq Atlas 12813