Version 5.4
Mus musculus Gene: Gpr119
Summary
InnateDB Gene IDBG-144156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr119
Gene Name G-protein coupled receptor 119
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051209
Encoded Proteins
IDBP-144158
G-protein coupled receptor 119
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147262:
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:48667979-48674478
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000053970 ENSMUSP00000060591
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0031210 phosphatidylcholine binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0030073 insulin secretion
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147262
View Gene Order
ENSBTAG00000014770
Not yet available
Pathways
NETPATH
REACTOME
REACT_230557
Incretin synthesis, secretion, and inactivation pathway
REACT_259776
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
REACT_247926
Metabolism of proteins pathway
REACT_206913
Peptide hormone metabolism pathway
REACT_253751
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23824
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
REACT_24019
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
REACT_23974
Incretin synthesis, secretion, and inactivation pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q7TQP3
TrEMBL
UniProt Splice Variant
Entrez Gene 236781
UniGene Mm.269129
RefSeq NM_181751 XM_006541488
OMIM
CCDS CCDS30113
HPRD
IMGT
MGI ID MGI:2668412
MGI Symbol Gpr119
EMBL AB233291 AL672042 AY288423 BC115557 BC115558
GenPept AAI15558 AAI15559 AAP72132 BAE80212 CAM27332
RNA Seq Atlas 236781

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca