Version 5.4
| Mus musculus Protein: Gpr119 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-144158.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Gpr119 | ||||||
| Protein Name | G-protein coupled receptor 119 | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000060591 | ||||||
| InnateDB Gene | IDBG-144156 (Gpr119) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. {ECO:0000269PubMed:17289847}. | ||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expression restricted to the beta-cells of pancreatic islets. {ECO:0000269PubMed:17070774, ECO:0000269PubMed:17289847}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:2668412 | ||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx |
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| PFAM |
PF00001
PF10320 |
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| PRINTS |
PR00237
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| PIRSF | |||||||
| SMART | |||||||
| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q7TQP3 | ||||||
| PhosphoSite | PhosphoSite-Q7TQP3 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 236781 | ||||||
| UniGene | Mm.269129 | ||||||
| RefSeq | NP_861416 | ||||||
| MGI ID | |||||||
| MGI Symbol | Gpr119 | ||||||
| OMIM | |||||||
| CCDS | CCDS30113 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AB233291 AL672042 AY288423 BC115557 BC115558 | ||||||
| GenPept | AAI15558 AAI15559 AAP72132 BAE80212 CAM27332 | ||||||