Version 5.4
Mus musculus Gene: Pbrm1
Summary
InnateDB Gene IDBG-144501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pbrm1
Gene Name polybromo 1
Synonyms 2610016F04Rik; AI507524; BAF180; Pb1
Species Mus musculus
Ensembl Gene ENSMUSG00000042323
Encoded Proteins
IDBP-144505
polybromo 1
IDBP-144750
polybromo 1
IDBP-144752
polybromo 1
IDBP-144754
polybromo 1
IDBP-256711
polybromo 1
IDBP-256713
polybromo 1
IDBP-256715
polybromo 1
IDBP-256717
polybromo 1
IDBP-256719
polybromo 1
IDBP-532582
polybromo 1
IDBP-532482
polybromo 1
IDBP-541948
polybromo 1
IDBP-537908
polybromo 1
IDBP-537420
polybromo 1
IDBP-537412
polybromo 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163939:
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:31019138-31121592
Strand Forward strand
Band B
Transcripts
ENSMUST00000022474 ENSMUSP00000022474
ENSMUST00000052239 ENSMUSP00000060476
ENSMUST00000022471 ENSMUSP00000022471
ENSMUST00000090214 ENSMUSP00000087682
ENSMUST00000112106 ENSMUSP00000107734
ENSMUST00000112098 ENSMUSP00000107727
ENSMUST00000112095 ENSMUSP00000107724
ENSMUST00000112094 ENSMUSP00000107723
ENSMUST00000112092 ENSMUSP00000107721
ENSMUST00000146325 ENSMUSP00000122805
ENSMUST00000144009 ENSMUSP00000123518
ENSMUST00000145497
ENSMUST00000136237 ENSMUSP00000119722
ENSMUST00000156628 ENSMUSP00000123546
ENSMUST00000123678 ENSMUSP00000120549
ENSMUST00000135704 ENSMUSP00000115505
ENSMUST00000156407
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0001890 placenta development
GO:0001974 blood vessel remodeling
GO:0003007 heart morphogenesis
GO:0003349 epicardium-derived cardiac endothelial cell differentiation
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0008285 negative regulation of cell proliferation
GO:0016568 chromatin modification
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060948 cardiac vascular smooth muscle cell development
GO:0060979 vasculogenesis involved in coronary vascular morphogenesis
Cellular Component
GO:0000776 kinetochore
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163939
View Gene Order
ENSBTAG00000014786
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_244207
RMTs methylate histone arginines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172623
Chromatin organization pathway
REACT_228108
RMTs methylate histone arginines pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3Z1M8
UniProt Splice Variant
Entrez Gene 66923
UniGene Mm.27913 Mm.413281 Mm.442229 Mm.444818 Mm.445686 Mm.473317
RefSeq NM_001081251 XM_006519402 XM_006519403 XM_006519404 XM_006519405 XM_006519406 XM_006519407 XM_006519408 XM_006519409 XM_006519410 XM_006519411 XM_006519412 XM_006519413 XM_006519414 XM_006519416 XM_006519418 XM_006519421 XM_006519423 XM_006519425 XM_006519426 XM_006519427
OMIM
CCDS CCDS36851
HPRD
IMGT
MGI ID MGI:1923998
MGI Symbol Pbrm1
EMBL AC154446 AC154727
GenPept
RNA Seq Atlas 66923

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca