Version 5.4
Mus musculus Gene: Gtf3c6
Summary
InnateDB Gene IDBG-145318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf3c6
Gene Name general transcription factor IIIC, polypeptide 6, alpha
Synonyms 2410016F19Rik; AU019813
Species Mus musculus
Ensembl Gene ENSMUSG00000019837
Encoded Proteins
IDBP-145320
general transcription factor IIIC, polypeptide 6, alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155115:
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:40249203-40257665
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000019982 ENSMUSP00000019982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
Cellular Component
GO:0000127 transcription factor TFIIIC complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000155115
View Gene Order
ENSBTAG00000016582
Not yet available
Cross-References
SwissProt Q9D8P7
TrEMBL Q9DB36
UniProt Splice Variant
Entrez Gene 67371
UniGene Mm.64104
RefSeq NM_026113
OMIM
CCDS CCDS23794
HPRD
IMGT
MGI ID MGI:1914621
MGI Symbol Gtf3c6
EMBL AK005261 AK007816 AK162053 AK168070 BC027260 BC048446
GenPept AAH27260 AAH48446 BAB23913 BAB25281 BAE36699 BAE40045
RNA Seq Atlas 67371

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca