Version 5.4
Mus musculus Gene: Nin
Summary
InnateDB Gene IDBG-145359.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nin
Gene Name ninein
Synonyms 3110068G20Rik; AI385615; AU024711; mKIAA1565
Species Mus musculus
Ensembl Gene ENSMUSG00000021068
Encoded Proteins
IDBP-145361
ninein
IDBP-145363
ninein
IDBP-145365
ninein
IDBP-626016
ninein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100503:
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:70011435-70111925
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000085314 ENSMUSP00000082422
ENSMUST00000021468 ENSMUSP00000021468
ENSMUST00000095666 ENSMUSP00000093327
ENSMUST00000169074 ENSMUSP00000129648
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019900 kinase binding
Biological Process
GO:0034454 microtubule anchoring at centrosome
GO:0090222 centrosome-templated microtubule nucleation
Cellular Component
GO:0000922 spindle pole
GO:0005730 nucleolus
GO:0005813 centrosome
GO:0005814 centriole
GO:0005874 microtubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100503
View Gene Order
ENSBTAG00000020281
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.244047 Mm.402700
RefSeq NM_001081453 NM_001286079 NM_008697 XM_006515527 XM_006515528 XM_006515529 XM_006515530 XM_006515531
OMIM
CCDS CCDS36468 CCDS36469
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca