Mus musculus Gene: Phf7
Summary
InnateDB Gene IDBG-145737.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phf7
Gene Name PHD finger protein 7
Synonyms 1700006H01Rik; 1700010P14Rik; AI427892; AW555949;
Species Mus musculus
Ensembl Gene ENSMUSG00000021902
Encoded Proteins
PHD finger protein 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000010318:
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:31237696-31251218
Strand Reverse strand
Band B
Transcripts
ENSMUST00000022459 ENSMUSP00000022459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9DAG9
TrEMBL A2RTI5
UniProt Splice Variant
Entrez Gene 71838
UniGene
RefSeq NM_027949
OMIM
CCDS CCDS26909
HPRD
IMGT
MGI ID MGI:1919088
MGI Symbol Phf7
EMBL AK005852 BC057174 BC132517 BC138571 CH466573
GenPept AAH57174 AAI32518 AAI38572 BAB24275 EDL24799
RNA Seq Atlas 71838