Mus musculus Gene: Ms4a8a
Summary
InnateDB Gene IDBG-145846.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ms4a8a
Gene Name membrane-spanning 4-domains, subfamily A, member 8A
Synonyms 2010004L09Rik; AI481240; CD20L5; Ms4a8;
Species Mus musculus
Ensembl Gene ENSMUSG00000024730
Encoded Proteins
membrane-spanning 4-domains, subfamily A, member 8A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
Ms4a8a expression is induced by TLR signalling in M2-like macrophages. Ms4a8a is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections.
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] MS4A8B expression is induced by TLR signalling in M2-like macrophages. MS4A8B is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections. (Demonstrated in mice)
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166959:
This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.3, among a cluster of family members. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11067471-11081102
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025636 ENSMUSP00000025636
ENSMUST00000187859
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q99N10
TrEMBL
UniProt Splice Variant
Entrez Gene 64381
UniGene
RefSeq NM_022430
OMIM
CCDS CCDS37921
HPRD
IMGT
MGI ID MGI:1927657
MGI Symbol Ms4a8a
EMBL AB026044 AC148321 AF237906 AK172700 AY039038 BC042719
GenPept AAH42719 AAK37415 AAK92698 BAB18756 BAE43134
RNA Seq Atlas 64381