Version 5.4
Homo sapiens Gene: MS4A8B
Summary
InnateDB Gene IDBG-49293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MS4A8B
Gene Name membrane-spanning 4-domains, subfamily A, member 8B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166959
Encoded Proteins
IDBP-49295
membrane-spanning 4-domains, subfamily A, member 8B
IDBP-585218
membrane-spanning 4-domains, subfamily A, member 8B
IDBP-596561
membrane-spanning 4-domains, subfamily A, member 8B
IDBP-602723
membrane-spanning 4-domains, subfamily A, member 8B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 22806454
MS4A8B expression is induced by TLR signalling in M2-like macrophages. MS4A8B is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections. (Demonstrated in mice)
InnateDB Annotation from Orthologs
Summary
PMID 22806454
[Mus musculus] Ms4a8a expression is induced by TLR signalling in M2-like macrophages. Ms4a8a is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections.
Entrez Gene
Summary This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.3, among a cluster of family members. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:60699574-60715811
Strand Forward strand
Band q12.2
Transcripts
ENST00000300226 ENSP00000300226
ENST00000450141
ENST00000533691
ENST00000532953
ENST00000533354
ENST00000529752 ENSP00000436857
ENST00000532816 ENSP00000435567
ENST00000534316
ENST00000525458 ENSP00000433200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024730
View Gene Order
ENSBTAG00000009289
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.150878
RefSeq NM_031457
HUGO
OMIM
CCDS CCDS7990
HPRD 08409
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca