Homo sapiens Gene: MS4A8B
Summary
InnateDB Gene IDBG-49293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MS4A8B
Gene Name membrane-spanning 4-domains, subfamily A, member 8B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166959
Encoded Proteins
membrane-spanning 4-domains, subfamily A, member 8B
membrane-spanning 4-domains, subfamily A, member 8B
membrane-spanning 4-domains, subfamily A, member 8B
membrane-spanning 4-domains, subfamily A, member 8B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
MS4A8B expression is induced by TLR signalling in M2-like macrophages. MS4A8B is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections. (Demonstrated in mice)
InnateDB Annotation from Orthologs
Summary
[Mus musculus] Ms4a8a expression is induced by TLR signalling in M2-like macrophages. Ms4a8a is expressed at the late stages of Trypanosoma congolense and Taenia crassiceps infections.
Entrez Gene
Summary This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.3, among a cluster of family members. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:60699574-60715811
Strand Forward strand
Band q12.2
Transcripts
ENST00000300226 ENSP00000300226
ENST00000450141
ENST00000533691
ENST00000532953
ENST00000533354
ENST00000529752 ENSP00000436857
ENST00000532816 ENSP00000435567
ENST00000534316
ENST00000525458 ENSP00000433200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.150878
RefSeq NM_031457
HUGO
OMIM
CCDS CCDS7990
HPRD 08409
IMGT
EMBL
GenPept
RNA Seq Atlas