Mus musculus Gene: Ms4a1
Summary
InnateDB Gene IDBG-146027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ms4a1
Gene Name membrane-spanning 4-domains, subfamily A, member 1
Synonyms AA960661; Cd20; Ly-44; Ms4a2;
Species Mus musculus
Ensembl Gene ENSMUSG00000024673
Encoded Proteins
membrane-spanning 4-domains, subfamily A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156738:
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11249675-11266241
Strand Reverse strand
Band A
Transcripts
ENSMUST00000169159 ENSMUSP00000126422
ENSMUST00000185851
ENSMUST00000187379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005154 epidermal growth factor receptor binding
GO:0023026 MHC class II protein complex binding
Biological Process
GO:0042113 B cell activation
Cellular Component
GO:0005615 extracellular space
GO:0005730 nucleolus
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
Hematopoietic cell lineage pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Hematopoietic cell lineage pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P19437
TrEMBL Q542S5 Q8BNW4
UniProt Splice Variant
Entrez Gene 12482
UniGene Mm.401796
RefSeq NM_007641
OMIM
CCDS CCDS37923
HPRD
IMGT
MGI ID MGI:88321
MGI Symbol Ms4a1
EMBL AK017903 AK041428 AK080040 AK080148 AK156033 AK171631 AK171638 AK171659 BC028322 CH466534 CT010253 M62541
GenPept AAA37394 AAH28322 BAB30996 BAC30944 BAC37812 BAC37833 BAE33554 BAE42576 BAE42578 BAE42593 CAJ18461 EDL41412
RNA Seq Atlas 12482