Version 5.4
Mus musculus Gene: Hacl1
Summary
InnateDB Gene IDBG-146898.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hacl1
Gene Name 2-hydroxyacyl-CoA lyase 1
Synonyms 1600020H07Rik; Hpcl; Phyh2
Species Mus musculus
Ensembl Gene ENSMUSG00000021884
Encoded Proteins
IDBP-146900
2-hydroxyacyl-CoA lyase 1
IDBP-537819
2-hydroxyacyl-CoA lyase 1
IDBP-541962
2-hydroxyacyl-CoA lyase 1
IDBP-535396
2-hydroxyacyl-CoA lyase 1
IDBP-624752
2-hydroxyacyl-CoA lyase 1
IDBP-624737
2-hydroxyacyl-CoA lyase 1
IDBP-624749
2-hydroxyacyl-CoA lyase 1
IDBP-624750
2-hydroxyacyl-CoA lyase 1
IDBP-624751
2-hydroxyacyl-CoA lyase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131373:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:31552905-31641286
Strand Reverse strand
Band B
Transcripts
ENSMUST00000022437 ENSMUSP00000022437
ENSMUST00000156431 ENSMUSP00000114922
ENSMUST00000140078
ENSMUST00000139501
ENSMUST00000127204 ENSMUSP00000120452
ENSMUST00000134626 ENSMUSP00000114879
ENSMUST00000128629 ENSMUSP00000125890
ENSMUST00000155210
ENSMUST00000156189
ENSMUST00000135751
ENSMUST00000167175 ENSMUSP00000128588
ENSMUST00000167066 ENSMUSP00000132913
ENSMUST00000165955 ENSMUSP00000129090
ENSMUST00000171414 ENSMUSP00000130268
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0005102 receptor binding
GO:0016829 lyase activity
GO:0016830 carbon-carbon lyase activity
GO:0030976 thiamine pyrophosphate binding
GO:0042802 identical protein binding
GO:0048037 cofactor binding
Biological Process
GO:0001561 fatty acid alpha-oxidation
GO:0006629 lipid metabolic process
GO:0051259 protein oligomerization
Cellular Component
GO:0005777 peroxisome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000131373
View Gene Order
ENSBTAG00000003718
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_260555
Alpha-oxidation of phytanate pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_246750
Peroxisomal lipid metabolism pathway
KEGG
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_17003
Alpha-oxidation of phytanate pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_16957
Peroxisomal lipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YZ54
UniProt Splice Variant
Entrez Gene 56794
UniGene
RefSeq NM_019975 XM_006519320
OMIM
CCDS CCDS26915
HPRD
IMGT
MGI ID MGI:1929657
MGI Symbol Hacl1
EMBL AC109509
GenPept
RNA Seq Atlas 56794

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca