Homo sapiens Gene: ACRBP
Summary
InnateDB Gene IDBG-14696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACRBP
Gene Name acrosin binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111644
Encoded Proteins
acrosin binding protein
acrosin binding protein
acrosin binding protein
acrosin binding protein
acrosin binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:6638075-6647460
Strand Reverse strand
Band p13.31
Transcripts
ENST00000229243 ENSP00000229243
ENST00000414226 ENSP00000402725
ENST00000540513
ENST00000542357
ENST00000536350 ENSP00000443153
ENST00000535884 ENSP00000445262
ENST00000544352
ENST00000546114 ENSP00000438656
ENST00000538524
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.123239
RefSeq NM_032489
HUGO
OMIM
CCDS CCDS8554
HPRD 16322
IMGT
EMBL
GenPept
RNA Seq Atlas