Version 5.4
Mus musculus Gene: Cep120
Summary
InnateDB Gene IDBG-147107.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep120
Gene Name centrosomal protein 120
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000048799
Encoded Proteins
IDBP-147109
centrosomal protein 120
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168944:
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:53681724-53744547
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000049811 ENSMUSP00000062433
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0008283 cell proliferation
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0022027 interkinetic nuclear migration
GO:0030953 astral microtubule organization
GO:0032880 regulation of protein localization
GO:0032886 regulation of microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168944
View Gene Order
ENSBTAG00000013184
Not yet available
Cross-References
SwissProt Q7TSG1
TrEMBL
UniProt Splice Variant
Entrez Gene 225523
UniGene Mm.193678 Mm.397605
RefSeq NM_178686 XM_006525874
OMIM
CCDS CCDS37822
HPRD
IMGT
MGI ID MGI:2147298
MGI Symbol Cep120
EMBL AK038916 AK044808 AK044952 AK047594 AK079319 BC046493 BC048590 BC053439
GenPept AAH46493 AAH48590 AAH53439 BAC30167 BAC32100 BAC32156 BAC33092 BAC37606
RNA Seq Atlas 225523

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca