Mus musculus Gene: Kcnj5
Summary
InnateDB Gene IDBG-147413.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnj5
Gene Name potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms GIRK4; Kir3.4
Species Mus musculus
Ensembl Gene ENSMUSG00000032034
Encoded Proteins
potassium inwardly-rectifying channel, subfamily J, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120457:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:32314783-32344237
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000034533 ENSMUSP00000034533
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005515 protein binding
GO:0015467 G-protein activated inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Inwardly rectifying K+ channels pathway
G protein gated Potassium channels pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Activation of GABAB receptors pathway
Potassium Channels pathway
GABA B receptor activation pathway
GABA receptor activation pathway
Neuronal System pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Transmission across Chemical Synapses pathway
Activation of G protein gated Potassium channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
GABA B receptor activation pathway
Activation of G protein gated Potassium channels pathway
Neuronal System pathway
GABA receptor activation pathway
G protein gated Potassium channels pathway
Activation of GABAB receptors pathway
Inwardly rectifying K+ channels pathway
Potassium Channels pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_010605 XM_006510039 XM_006510040 XM_006510041
OMIM
CCDS CCDS22952
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas