Version 5.4
| Homo sapiens Gene: KCNJ5 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-75990.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | KCNJ5 | ||||||||||||||||||
| Gene Name | potassium inwardly-rectifying channel, subfamily J, member 5 | ||||||||||||||||||
| Synonyms | CIR; GIRK4; KATP1; KIR3.4; LQT13 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000120457 | ||||||||||||||||||
| Encoded Proteins |
potassium inwardly-rectifying channel, subfamily J, member 5
potassium inwardly-rectifying channel, subfamily J, member 5
potassium inwardly-rectifying channel, subfamily J, member 5
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:128891356-128921035 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q24.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
GABA B receptor activation pathway
Activation of G protein gated Potassium channels pathway
Neuronal System pathway
GABA receptor activation pathway
G protein gated Potassium channels pathway
Activation of GABAB receptors pathway
Inwardly rectifying K+ channels pathway
Potassium Channels pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | P48544 | ||||||||||||||||||
| TrEMBL | H9A8K9 H9A8L0 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 3762 | ||||||||||||||||||
| UniGene | Hs.444595 Hs.632109 | ||||||||||||||||||
| RefSeq | NM_000890 XM_005271543 | ||||||||||||||||||
| HUGO | HGNC:6266 | ||||||||||||||||||
| OMIM | 600734 | ||||||||||||||||||
| CCDS | CCDS8479 | ||||||||||||||||||
| HPRD | 09010 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AK312837 AP000920 BC069386 BC069482 BC069499 BC069571 BC074838 BC074839 D50134 JN859132 JN859133 L47208 U39195 U52154 X83582 | ||||||||||||||||||
| GenPept | AAB07045 AAB07269 AAB53093 AAH69386 AAH69482 AAH69499 AAH69571 AAH74838 AAH74839 AFB82769 AFB82770 BAA08814 BAG35691 CAA58565 | ||||||||||||||||||
| RNA Seq Atlas | 3762 | ||||||||||||||||||