Mus musculus Gene: Actl7b
InnateDB Gene IDBG-148772.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Actl7b
Gene Name actin-like 7b
Synonyms Tact1;
Species Mus musculus
Ensembl Gene ENSMUSG00000070980
Encoded Proteins
actin-like 7b
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148156:
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:56740005-56741443
Strand Reverse strand
Band B3
ENSMUST00000095080 ENSMUSP00000092693
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Homo sapiens
Bos taurus
Gene ID
Gene Order
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
SwissProt Q9QY83
UniProt Splice Variant
Entrez Gene 11471
UniGene Mm.251434 Mm.467010
RefSeq NM_025271
MGI ID MGI:1343053
MGI Symbol Actl7b
EMBL AB023062 AB079643 AF113520 AL807762 BC116815 BC116817 CH466565
GenPept AAF18299 AAI16816 AAI16818 BAA90821 BAC07296 CAM25710 EDL02259
RNA Seq Atlas 11471