Mus musculus Gene: Gpr50
Summary
InnateDB Gene IDBG-150845.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr50
Gene Name G-protein-coupled receptor 50
Synonyms H9;
Species Mus musculus
Ensembl Gene ENSMUSG00000056380
Encoded Proteins
G-protein-coupled receptor 50
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102195:
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:71663667-71669257
Strand Forward strand
Band A7.3
Transcripts
ENSMUST00000070449 ENSMUSP00000064608
ENSMUST00000144712
ENSMUST00000131554
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0008502 melatonin receptor activity
GO:0042802 identical protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O88495
TrEMBL
UniProt Splice Variant
Entrez Gene 14765
UniGene Mm.33336 Mm.474998
RefSeq NM_010340
OMIM
CCDS CCDS30181
HPRD
IMGT
MGI ID MGI:1333877
MGI Symbol Gpr50
EMBL AF065145 AK132272 AL840624 BC137982 CH466624
GenPept AAC21462 AAI37983 BAE21072 EDL26572
RNA Seq Atlas 14765