Mus musculus Gene: Cetn2
Summary
InnateDB Gene IDBG-151407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cetn2
Gene Name centrin 2
Synonyms 1110034A02Rik; AI326150; Calt; caltractin;
Species Mus musculus
Ensembl Gene ENSMUSG00000031347
Encoded Proteins
centrin 2
centrin 2
centrin 2
centrin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147400:
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:72913532-72918411
Strand Reverse strand
Band A7.3
Transcripts
ENSMUST00000033713 ENSMUSP00000033713
ENSMUST00000114551 ENSMUSP00000110198
ENSMUST00000114550 ENSMUSP00000110197
ENSMUST00000152200 ENSMUSP00000117704
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008026 ATP-dependent helicase activity
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032795 heterotrimeric G-protein binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006289 nucleotide-excision repair
GO:0007067 mitotic nuclear division
GO:0007099 centriole replication
GO:0007283 spermatogenesis
GO:0032465 regulation of cytokinesis
Cellular Component
GO:0005622 intracellular
GO:0005813 centrosome
GO:0005814 centriole
GO:0005929 cilium
GO:0032391 photoreceptor connecting cilium
GO:0036064 ciliary basal body
GO:0071942 XPC complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Recruitment of mitotic centrosome proteins and complexes pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Cell Cycle pathway
Mitotic G2-G2/M phases pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Centrosome maturation pathway
KEGG
Nucleotide excision repair pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Loss of Nlp from mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Mitotic G2-G2/M phases pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Centrosome maturation pathway
KEGG
Nucleotide excision repair pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL B1AUQ7 Z4YJH1
UniProt Splice Variant
Entrez Gene 26370
UniGene Mm.24643
RefSeq NM_019405
OMIM
CCDS CCDS41003
HPRD
IMGT
MGI ID MGI:1347085
MGI Symbol Cetn2
EMBL AL671908
GenPept
RNA Seq Atlas 26370