InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CETN2

Summary

InnateDB Gene

IDBG-631952.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CETN2

Gene Name

Centrin-2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007844

Encoded Proteins

IDBP-683533

Centrin-2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147400:
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:35382935-35386969

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000010319

ENSBTAP00000010319

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0008026	ATP-dependent helicase activity
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0032795	heterotrimeric G-protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006289	nucleotide-excision repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007049	cell cycle
GO:0007067	mitotic nuclear division
GO:0007099	centriole replication
GO:0007283	spermatogenesis
GO:0032465	regulation of cytokinesis
GO:0051301	cell division

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0005856	cytoskeleton
GO:0005929	cilium
GO:0032391	photoreceptor connecting cilium
GO:0036064	ciliary basal body
GO:0071942	XPC complex