Homo sapiens Gene: APBB2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-15151.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | APBB2 | ||||||||||||||||||||||
Gene Name | amyloid beta (A4) precursor protein-binding, family B, member 2 | ||||||||||||||||||||||
Synonyms | FE65L; FE65L1 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000163697 | ||||||||||||||||||||||
Encoded Proteins |
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
amyloid beta (A4) precursor protein-binding, family B, member 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer\'s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 4:40810027-41216714 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | p13 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Hs.479602 Hs.720643 Hs.734795 | ||||||||||||||||||||||
RefSeq | NM_001166050 NM_001166051 NM_001166052 NM_001166053 NM_001166054 NM_004307 NM_173075 XM_006714005 XM_006714006 XM_006714007 XM_006714008 XM_006714009 XM_006714010 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS43224 CCDS54760 CCDS54761 CCDS54762 | ||||||||||||||||||||||
HPRD | 04088 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||