Version 5.4
Mus musculus Gene: Nmd3
Summary
InnateDB Gene IDBG-151608.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmd3
Gene Name NMD3 homolog (S. cerevisiae)
Synonyms C87860
Species Mus musculus
Ensembl Gene ENSMUSG00000027787
Encoded Proteins
IDBP-151610
NMD3 homolog (S. cerevisiae)
IDBP-537148
NMD3 homolog (S. cerevisiae)
IDBP-532634
NMD3 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169251:
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:69721985-69749042
Strand Forward strand
Band E1
Transcripts
ENSMUST00000029358 ENSMUSP00000029358
ENSMUST00000149680
ENSMUST00000143041 ENSMUSP00000116113
ENSMUST00000135266
ENSMUST00000127211
ENSMUST00000143249 ENSMUSP00000115736
ENSMUST00000150210
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030674 protein binding, bridging
GO:0043023 ribosomal large subunit binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0015031 protein transport
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169251
View Gene Order
ENSBTAG00000016228
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_133787
OMIM
CCDS CCDS17407
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca