Version 5.4
| Mus musculus Gene: Fat1 | |||||||||||||||||||||
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| Summary | |||||||||||||||||||||
| InnateDB Gene | IDBG-151656.6 | ||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
| Gene Symbol | Fat1 | ||||||||||||||||||||
| Gene Name | FAT tumor suppressor homolog 1 (Drosophila) | ||||||||||||||||||||
| Synonyms | 2310038E12Rik; AU023433; Fath; mFat1 | ||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000070047 | ||||||||||||||||||||
| Encoded Proteins |
FAT tumor suppressor homolog 1 (Drosophila)
FAT tumor suppressor homolog 1 (Drosophila)
FAT tumor suppressor homolog 1 (Drosophila)
FAT tumor suppressor homolog 1 (Drosophila)
FAT tumor suppressor homolog 1 (Drosophila)
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| Protein Structure | |||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083857:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||
| Genomic Location | Chromosome 8:44935447-45052257 | ||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||
| Band | B1.1 | ||||||||||||||||||||
| Transcripts | |||||||||||||||||||||
| Interactions | |||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
| NETPATH | |||||||||||||||||||||
| REACTOME | |||||||||||||||||||||
| KEGG | |||||||||||||||||||||
| INOH | |||||||||||||||||||||
| PID NCI | |||||||||||||||||||||
| Cross-References | |||||||||||||||||||||
| SwissProt | |||||||||||||||||||||
| TrEMBL | F2Z4A3 Q6X4A1 Q80XT9 | ||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||
| Entrez Gene | 14107 | ||||||||||||||||||||
| UniGene | |||||||||||||||||||||
| RefSeq | XM_006509271 XM_006509274 XM_006509277 NM_001081286 | ||||||||||||||||||||
| OMIM | |||||||||||||||||||||
| CCDS | CCDS52547 | ||||||||||||||||||||
| HPRD | |||||||||||||||||||||
| IMGT | |||||||||||||||||||||
| MGI ID | MGI:109168 | ||||||||||||||||||||
| MGI Symbol | Fat1 | ||||||||||||||||||||
| EMBL | AC119214 AC158352 AY256848 BC041794 | ||||||||||||||||||||
| GenPept | AAH41794 AAP82173 | ||||||||||||||||||||
| RNA Seq Atlas | 14107 | ||||||||||||||||||||