Mus musculus Gene: Tomm40
Summary
InnateDB Gene IDBG-152166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tomm40
Gene Name translocase of outer mitochondrial membrane 40 homolog (yeast)
Synonyms AW539759; Mom35; Tom40;
Species Mus musculus
Ensembl Gene ENSMUSG00000002984
Encoded Proteins
translocase of outer mitochondrial membrane 40 homolog (yeast)
translocase of outer mitochondrial membrane 40 homolog (yeast)
translocase of outer mitochondrial membrane 40 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130204:
TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria (Humphries et al., 2005 [PubMed 15644312]).[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:19701313-19715438
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000032555 ENSMUSP00000032555
ENSMUST00000093552 ENSMUSP00000104090
ENSMUST00000174476
ENSMUST00000172705 ENSMUSP00000133975
ENSMUST00000173966
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015288 porin activity
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0006811 ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005742 mitochondrial outer membrane translocase complex
GO:0016021 integral component of membrane
GO:0032592 integral component of mitochondrial membrane
GO:0046930 pore complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
KEGG
Amyotrophic lateral sclerosis (ALS) pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of proteins pathway
Mitochondrial protein import pathway
Mitochondrial protein import pathway
Metabolism of proteins pathway
KEGG
Amyotrophic lateral sclerosis (ALS) pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL G3UY77
UniProt Splice Variant
Entrez Gene 53333
UniGene Mm.440173
RefSeq NM_001109748 NM_016871
OMIM
CCDS CCDS52062
HPRD
IMGT
MGI ID MGI:1858259
MGI Symbol Tomm40
EMBL AC149282
GenPept
RNA Seq Atlas 53333