Version 5.4
Mus musculus Gene: Secisbp2
Summary
InnateDB Gene IDBG-152363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Secisbp2
Gene Name SECIS binding protein 2
Synonyms 2210413N07Rik; 2810012K13Rik; SBP2
Species Mus musculus
Ensembl Gene ENSMUSG00000035139
Encoded Proteins
IDBP-152365
SECIS binding protein 2
IDBP-261104
SECIS binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187742:
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:51651697-51684044
Strand Forward strand
Band A5
Transcripts
ENSMUST00000040117 ENSMUSP00000045740
ENSMUST00000110044 ENSMUSP00000105671
ENSMUST00000154202
ENSMUST00000127360
ENSMUST00000146011
ENSMUST00000153877
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0035368 selenocysteine insertion sequence binding
GO:0043021 ribonucleoprotein complex binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187742
View Gene Order
ENSBTAG00000001939
Not yet available
Cross-References
SwissProt
TrEMBL Q8BYU9
UniProt Splice Variant
Entrez Gene 75420
UniGene Mm.275981
RefSeq NM_029279 XM_006516963
OMIM
CCDS CCDS36665
HPRD
IMGT
MGI ID MGI:1922670
MGI Symbol Secisbp2
EMBL AC126547 AK037988
GenPept BAC29914
RNA Seq Atlas 75420

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca