Mus musculus Gene: Pms1
Summary
InnateDB Gene IDBG-153962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pms1
Gene Name postmeiotic segregation increased 1 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026098
Encoded Proteins
postmeiotic segregation increased 1 (S. cerevisiae)
postmeiotic segregation increased 1 (S. cerevisiae)
postmeiotic segregation increased 1 (S. cerevisiae)
postmeiotic segregation increased 1 (S. cerevisiae)
postmeiotic segregation increased 1 (S. cerevisiae)
postmeiotic segregation increased 1 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064933:
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:53189187-53297018
Strand Reverse strand
Band C1.1
Transcripts
ENSMUST00000027267 ENSMUSP00000027267
ENSMUST00000135246 ENSMUSP00000119632
ENSMUST00000142922
ENSMUST00000128337 ENSMUSP00000115352
ENSMUST00000133358 ENSMUSP00000122418
ENSMUST00000126590 ENSMUSP00000120670
ENSMUST00000126412 ENSMUSP00000120340
ENSMUST00000188890
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0030983 mismatched DNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006298 mismatch repair
GO:0042493 response to drug
Cellular Component
GO:0032389 MutLalpha complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL D3Z012
UniProt Splice Variant
Entrez Gene 227099
UniGene Mm.60499
RefSeq NM_153556 XM_006495938 XM_006495939 XM_006495940 XM_006495941 XM_006495942
OMIM
CCDS CCDS14951
HPRD
IMGT
MGI ID MGI:1202302
MGI Symbol Pms1
EMBL AC129288 AC153650
GenPept
RNA Seq Atlas 227099