Homo sapiens Gene: WDR81
Summary
InnateDB Gene IDBG-15476.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR81
Gene Name WD repeat domain 81
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167716
Encoded Proteins
WD repeat domain 81
WD repeat domain 81
WD repeat domain 81
WD repeat domain 81
WD repeat domain 81
WD repeat domain 81
WD repeat domain 81
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a multi-domain transmembrane protein, which is predominantly expressed in the brain. Mutations in this gene are associated with autosomal recessive cerebellar ataxia, mental retardation, and dysequilibrium syndrome-2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:1716523-1738599
Strand Forward strand
Band p13.3
Transcripts
ENST00000309182 ENSP00000312074
ENST00000409644 ENSP00000386609
ENST00000455636 ENSP00000395226
ENST00000446363 ENSP00000401560
ENST00000419248 ENSP00000407845
ENST00000418841 ENSP00000395198
ENST00000437219 ENSP00000391074
ENST00000468539 ENSP00000460742
ENST00000492901
ENST00000464528
ENST00000474958 ENSP00000466240
ENST00000479966
ENST00000495411
ENST00000575206 ENSP00000458811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0008152 metabolic process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.234572
RefSeq NM_001163673 NM_001163809 NM_001163811 NM_152348 XM_005256454 XM_006725254
HUGO
OMIM
CCDS CCDS54061 CCDS54062 CCDS54063
HPRD 08748
IMGT
EMBL
GenPept
RNA Seq Atlas