Version 5.4
Mus musculus Gene: Slc34a1
Summary
InnateDB Gene IDBG-155530.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc34a1
Gene Name solute carrier family 34 (sodium phosphate), member 1
Synonyms NaPi-IIa; Npt2; Npt2a; Slc17a2
Species Mus musculus
Ensembl Gene ENSMUSG00000021490
Encoded Proteins
IDBP-155532
solute carrier family 34 (sodium phosphate), member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131183:
This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:55399648-55414695
Strand Forward strand
Band B1
Transcripts
ENSMUST00000057167 ENSMUSP00000059138
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015321 sodium-dependent phosphate transmembrane transporter activity
GO:0030165 PDZ domain binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001503 ossification
GO:0001822 kidney development
GO:0006817 phosphate ion transport
GO:0007584 response to nutrient
GO:0009100 glycoprotein metabolic process
GO:0010288 response to lead ion
GO:0032026 response to magnesium ion
GO:0032355 response to estradiol
GO:0033189 response to vitamin A
GO:0035864 response to potassium ion
GO:0042431 indole metabolic process
GO:0042493 response to drug
GO:0043434 response to peptide hormone
GO:0044341 sodium-dependent phosphate transport
GO:0045838 positive regulation of membrane potential
GO:0046686 response to cadmium ion
GO:0046689 response to mercury ion
GO:0046849 bone remodeling
GO:0051260 protein homooligomerization
GO:0055062 phosphate ion homeostasis
GO:0060416 response to growth hormone
GO:0071107 response to parathyroid hormone
GO:0071248 cellular response to metal ion
GO:0071374 cellular response to parathyroid hormone stimulus
GO:0072350 tricarboxylic acid metabolic process
GO:0072734 cellular response to staurosporine
GO:0097066 response to thyroid hormone
GO:0097187 dentinogenesis
GO:1901128 gentamycin metabolic process
GO:1901652 response to peptide
GO:1901684 arsenate ion transmembrane transport
GO:2000120 positive regulation of sodium-dependent phosphate transport
GO:2000187 positive regulation of phosphate transmembrane transport
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0031226 intrinsic component of plasma membrane
GO:0031526 brush border membrane
GO:0031988 membrane-bounded vesicle
GO:0045121 membrane raft
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000131183
View Gene Order
ENSBTAG00000020351
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19411
Type II Na+/Pi cotransporters pathway
REACT_19275
Sodium-coupled phosphate cotransporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q8C012 Q9D2V6
UniProt Splice Variant
Entrez Gene 20505
UniGene Mm.276355
RefSeq NM_011392 XM_006517176 XM_006517178
OMIM
CCDS CCDS49271
HPRD
IMGT
MGI ID MGI:1345284
MGI Symbol Slc34a1
EMBL AB163921 AB163922 AK018740 AK032618 BC020529 CT009762
GenPept AAH20529 BAB31381 BAC27952 BAE48723 BAE48724
RNA Seq Atlas 20505

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca