Version 5.4
| Mus musculus Gene: Lrrc8a | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-155882.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Lrrc8a | ||||||||
| Gene Name | leucine rich repeat containing 8A | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000007476 | ||||||||
| Encoded Proteins |
leucine rich repeat containing 8A
leucine rich repeat containing 8A
predicted gene, 28035
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136802:
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 2:30237715-30263790 | ||||||||
| Strand | Forward strand | ||||||||
| Band | B | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | Q80WG5 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 241296 | ||||||||
| UniGene | Mm.389232 Mm.475219 | ||||||||
| RefSeq | NM_177725 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15875 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2652847 | ||||||||
| MGI Symbol | Lrrc8a | ||||||||
| EMBL | AL845258 BC048152 CH466542 | ||||||||
| GenPept | CAM20568 EDL08450 | ||||||||
| RNA Seq Atlas | 241296 | ||||||||