Mus musculus Gene: Hgfac
Summary
InnateDB Gene IDBG-156529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hgfac
Gene Name hepatocyte growth factor activator
Synonyms HGFA;
Species Mus musculus
Ensembl Gene ENSMUSG00000029102
Encoded Proteins
hepatocyte growth factor activator
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109758:
The protein encoded by this gene belongs to peptidase family S1. It is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. [provided by RefSeq, Jul 2008]
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:35041553-35048436
Strand Forward strand
Band B2
Transcripts
ENSMUST00000030985 ENSMUSP00000030985
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9R098
TrEMBL A8C1W3 Q545J3
UniProt Splice Variant
Entrez Gene 54426
UniGene Mm.481206
RefSeq NM_019447 XM_006504031 XM_006504033
OMIM
CCDS CCDS19223
HPRD
IMGT
MGI ID MGI:1859281
MGI Symbol Hgfac
EMBL AB009294 AF099017 AF224724 AK007987 AK149522
GenPept AAF02489 AAF34712 BAB25391 BAE28936 BAF80627
RNA Seq Atlas 54426