Version 5.4
| Mus musculus Protein: Hgfac | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-156531.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Hgfac | ||||||||
| Protein Name | hepatocyte growth factor activator | ||||||||
| Synonyms | HGFA; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000030985 | ||||||||
| InnateDB Gene | IDBG-156529 (Hgfac) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. {ECO:0000250}. | ||||||||
| Subcellular Localization | Secreted {ECO:0000250}. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1859281 | ||||||||
| InterPro |
IPR000001
Kringle IPR000083 Fibronectin, type I IPR000562 Fibronectin, type II, collagen-binding IPR000742 Epidermal growth factor-like domain IPR001254 Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR009003 Trypsin-like cysteine/serine peptidase domain IPR013806 Kringle-like fold IPR014394 Coagulation factor XIIa/hepatocyte growth factor activator |
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| PFAM |
PF00051
PF00039 PF00040 PF00008 PF00089 |
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| PRINTS |
PR00722
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| PIRSF |
PIRSF001146
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| SMART |
SM00130
SM00058 SM00059 SM00181 SM00020 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9R098 | ||||||||
| PhosphoSite | PhosphoSite-Q9R098 | ||||||||
| TrEMBL | Q545J3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 54426 | ||||||||
| UniGene | Mm.481206 | ||||||||
| RefSeq | NP_062320 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Hgfac | ||||||||
| OMIM | |||||||||
| CCDS | CCDS19223 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB009294 AF099017 AF224724 AK007987 AK149522 | ||||||||
| GenPept | AAF02489 AAF34712 BAB25391 BAE28936 BAF80627 | ||||||||