Version 5.4
Mus musculus Gene: Rab27b
Summary
InnateDB Gene IDBG-156998.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab27b
Gene Name RAB27b, member RAS oncogene family
Synonyms 2310021G14Rik; B130064M09Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024511
Encoded Proteins
IDBP-157002
RAB27b, member RAS oncogene family
IDBP-401271
RAB27b, member RAS oncogene family
IDBP-401272
RAB27b, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000041353:
Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:69979131-70141605
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000069749 ENSMUSP00000068349
ENSMUST00000121693 ENSMUSP00000114094
ENSMUST00000117692 ENSMUSP00000112807
ENSMUST00000127217
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0017157 regulation of exocytosis
GO:0045921 positive regulation of exocytosis
GO:0071985 multivesicular body sorting pathway
Cellular Component
GO:0005622 intracellular
GO:0005794 Golgi apparatus
GO:0005795 Golgi stack
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0030140 trans-Golgi network transport vesicle
GO:0030667 secretory granule membrane
GO:0032585 multivesicular body membrane
GO:0042589 zymogen granule membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000041353
View Gene Order
ENSBTAG00000002788
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04972
Pancreatic secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt Q99P58
TrEMBL Q549X4
UniProt Splice Variant
Entrez Gene 80718
UniGene Mm.246753 Mm.406668 Mm.407003
RefSeq NM_001082553 XM_006526362 XM_006526363 XM_006526364 NM_030554
OMIM
CCDS CCDS29331
HPRD
IMGT
MGI ID MGI:1931295
MGI Symbol Rab27b
EMBL AB067775 AB120512 AB232623 AF328893 AK049854 AY010898 BC032928 CH466528
GenPept AAG45502 AAH32928 AAK11242 BAB86914 BAC33958 BAC87832 BAF02885 EDL09585 EDL09586
RNA Seq Atlas 80718

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca