Version 5.4
Homo sapiens Gene: EMG1
Summary
InnateDB Gene IDBG-15773.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EMG1
Gene Name EMG1 nucleolar protein homolog (S. cerevisiae)
Synonyms C2F; Grcc2f; NEP1
Species Homo sapiens
Ensembl Gene ENSG00000126749
Encoded Proteins
IDBP-808186
cDNA FLJ60792, highly similar to Probable ribosome biogenesis protein NEP1
IDBP-808302
EMG1 N1-specific pseudouridine methyltransferase
IDBP-808299
EMG1 N1-specific pseudouridine methyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:6970893-6976619
Strand Forward strand
Band p13.31
Transcripts
ENST00000261406 ENSP00000476966
ENST00000539196 ENSP00000479546
ENST00000599672 ENSP00000470560
ENST00000611981
ENST00000620255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 22 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0019843 rRNA binding
GO:0044822 poly(A) RNA binding
GO:0070037 rRNA (pseudouridine) methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0031167 rRNA methylation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_006331
HUGO
OMIM
CCDS CCDS73430
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca