InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EMG1

Summary

InnateDB Protein

IDBP-808299.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EMG1

Protein Name

EMG1 N1-specific pseudouridine methyltransferase

Synonyms

C2F; Grcc2f; NEP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000470560

InnateDB Gene

IDBG-15773 (EMG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.

Experimentally validated
Total	25 [view]
Protein-Protein	22 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0008168	methyltransferase activity
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding
GO:0070037	rRNA (pseudouridine) methyltransferase activity

Biological Process

GO:0006364	rRNA processing
GO:0031167	rRNA methylation
GO:0042274	ribosomal small subunit biogenesis

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1

PFAM

PF03587

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q92979

PhosphoSite

PhosphoSite-Q92979

TrEMBL

UniProt Splice Variant

Entrez Gene

10436

UniGene

RefSeq

NP_006322

HUGO

HGNC:16912

OMIM

611531

CCDS

CCDS73430

HPRD

IMGT

EMBL

BC055314 U47924 U72514

GenPept

AAB51325 AAC51641 AAH55314