Version 5.4
Homo sapiens Gene: LPCAT3
Summary
InnateDB Gene IDBG-15806.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPCAT3
Gene Name lysophosphatidylcholine acyltransferase 3
Synonyms C3F; LPCAT; LPLAT 5; LPSAT; MBOAT5; nessy; OACT5
Species Homo sapiens
Ensembl Gene ENSG00000111684
Encoded Proteins
IDBP-15808
lysophosphatidylcholine acyltransferase 3
IDBP-587358
lysophosphatidylcholine acyltransferase 3
IDBP-596534
lysophosphatidylcholine acyltransferase 3
IDBP-586636
lysophosphatidylcholine acyltransferase 3
IDBP-593090
lysophosphatidylcholine acyltransferase 3
IDBP-583789
lysophosphatidylcholine acyltransferase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:6976186-7018510
Strand Reverse strand
Band p13.31
Transcripts
ENST00000261407 ENSP00000261407
ENST00000535479 ENSP00000438765
ENST00000535021
ENST00000540090 ENSP00000442454
ENST00000543794 ENSP00000443166
ENST00000536797 ENSP00000440550
ENST00000537179
ENST00000538987
ENST00000540060
ENST00000536971
ENST00000545459
ENST00000538910 ENSP00000437827
ENST00000620843
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0008152 metabolic process
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0097006 regulation of plasma lipoprotein particle levels
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004270
View Gene Order
ENSBTAG00000013127
Not yet available
Pathways
NETPATH
REACTOME
REACT_120829
Acyl chain remodelling of PC pathway
REACT_121384
Acyl chain remodelling of PS pathway
REACT_121369
Acyl chain remodelling of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.655248
RefSeq NM_005768
HUGO
OMIM
CCDS CCDS8572
HPRD 12816
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca