Version 5.4
Homo sapiens Gene: RRN3
Summary
InnateDB Gene IDBG-15872.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRN3
Gene Name RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000085721
Encoded Proteins
IDBP-15874
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
IDBP-24167
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
IDBP-369504
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
IDBP-746453
IDBP-754328
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:15060022-15094317
Strand Reverse strand
Band p13.11
Transcripts
ENST00000198767 ENSP00000198767
ENST00000327307 ENSP00000318484
ENST00000429751 ENSP00000402027
ENST00000564131 ENSP00000454238
ENST00000561685
ENST00000563559 ENSP00000454530
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005488 binding
GO:0070063 RNA polymerase binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006352 DNA-templated transcription, initiation
GO:0006360 transcription from RNA polymerase I promoter
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006413 translational initiation
GO:0007000 nucleolus organization
GO:0007028 cytoplasm organization
GO:0008283 cell proliferation
GO:0010467 gene expression
GO:0042254 ribosome biogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048872 homeostasis of number of cells
GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:2000142 regulation of DNA-dependent transcription, initiation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022682
View Gene Order
ENSBTAG00000004804
Not yet available
Pathways
NETPATH
REACTOME
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
mtor_4pathway
mTOR signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.460078
RefSeq NM_001301064 NM_018427 XM_005255375
HUGO
OMIM
CCDS CCDS10559 CCDS73833
HPRD 12004
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca