Mus musculus Gene: Il1rapl1
InnateDB Gene IDBG-159079.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il1rapl1
Gene Name interleukin 1 receptor accessory protein-like 1
Species Mus musculus
Ensembl Gene ENSMUSG00000052372
Encoded Proteins
interleukin 1 receptor accessory protein-like 1
interleukin 1 receptor accessory protein-like 1
interleukin 1 receptor accessory protein-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
[Homo sapiens] IL37 acts as an extracellular cytokine to inhibit innate inflammation by binding to IL18R1 and then using IL1RAPL1 for its anti-inflammatory properties.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169306:
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:86740870-88115645
Strand Reverse strand
Band C1
ENSMUST00000078875 ENSMUSP00000077915
ENSMUST00000113966 ENSMUSP00000109599
ENSMUST00000113964 ENSMUSP00000109597
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0045920 negative regulation of exocytosis
Cellular Component
GO:0005886 plasma membrane
Homo sapiens
Gene ID
Gene Order
UniProt Splice Variant
Entrez Gene 331461
UniGene Mm.121680 Mm.400887 Mm.409099 Mm.426143
RefSeq NM_001160403 XM_006528100
MGI ID MGI:2687319
MGI Symbol Il1rapl1
EMBL AL627409 AL672059 AL731705 AL844869 AL844900 AL954362 BC119580 BX005231 BX088567 BX649618 BX890584 CR538724
GenPept AAI19581
RNA Seq Atlas 331461