|Mus musculus Gene: Stc2|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||stanniocalcin 2|
|Synonyms||AW125853; mustc2; Stc2l;|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113739:
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 11:31357307-31370074|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|UniGene||Mm.32506 Mm.442854 Mm.442921|
|EMBL||AF031035 AF056244 AK010318 BC012206 CH466604|
|GenPept||AAC27507 AAD01921 AAH12206 BAB26849 EDL23779|
|RNA Seq Atlas||20856|