Version 5.4
| Mus musculus Gene: Slc18a1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-159699.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Slc18a1 | ||||||||||
| Gene Name | solute carrier family 18 (vesicular monoamine), member 1 | ||||||||||
| Synonyms | 4832416I10Rik; Vat1; Vmat1 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000036330 | ||||||||||
| Encoded Proteins |
solute carrier family 18 (vesicular monoamine), member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000036565:
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 8:69037711-69089235 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | B3.3 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Na+/Cl- dependent neurotransmitter transporters pathway
Transmembrane transport of small molecules pathway
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| KEGG |
Parkinson's disease pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Na+/Cl- dependent neurotransmitter transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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| KEGG |
Parkinson's disease pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q8R090 | ||||||||||
| TrEMBL | Q32XG7 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 110877 | ||||||||||
| UniGene | Mm.19301 | ||||||||||
| RefSeq | NM_153054 XM_006509534 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS22344 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:106684 | ||||||||||
| MGI Symbol | Slc18a1 | ||||||||||
| EMBL | AY779336 BC027192 BC031146 CH466569 | ||||||||||
| GenPept | AAH27192 AAH31146 AAX19142 EDL28728 | ||||||||||
| RNA Seq Atlas | 110877 | ||||||||||