Version 5.4
Mus musculus Gene: Snrpa
Summary
InnateDB Gene IDBG-160103.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Snrpa
Gene Name small nuclear ribonucleoprotein polypeptide A
Synonyms C430021M15Rik; Rnu1a-1; Rnu1a1; U1-A; U1A
Species Mus musculus
Ensembl Gene ENSMUSG00000061479
Encoded Proteins
IDBP-160105
small nuclear ribonucleoprotein polypeptide A
IDBP-401234
small nuclear ribonucleoprotein polypeptide A
IDBP-537198
small nuclear ribonucleoprotein polypeptide A
IDBP-532150
small nuclear ribonucleoprotein polypeptide A
IDBP-626478
small nuclear ribonucleoprotein polypeptide A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077312:
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5\' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27187005-27196271
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000080356 ENSMUSP00000079228
ENSMUST00000122202 ENSMUSP00000113678
ENSMUST00000148491
ENSMUST00000126211 ENSMUSP00000115335
ENSMUST00000141378 ENSMUSP00000119818
ENSMUST00000163311 ENSMUSP00000131897
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0017069 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000077312
View Gene Order
ENSBTAG00000009077
Not yet available
Pathways
NETPATH
REACTOME
REACT_249110
mRNA Splicing pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
REACT_205948
mRNA Splicing - Major Pathway pathway
REACT_206725
mRNA Splicing pathway
REACT_226022
Gene Expression pathway
REACT_226302
Processing of Capped Intron-Containing Pre-mRNA pathway
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt Q62189
TrEMBL D3Z0S6
UniProt Splice Variant
Entrez Gene 53607
UniGene Mm.435544
RefSeq XM_003688896 NM_001046637 NM_001285825 NM_015782 XM_356179 XM_990056
OMIM
CCDS CCDS21014
HPRD
IMGT
MGI ID MGI:1855690
MGI Symbol Snrpa
EMBL AC157553 AC157561 BC003229 BC094006 BC096648 L15447
GenPept AAC37611 AAH03229 AAH94006 AAH96648
RNA Seq Atlas 53607

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca