Version 5.4
Mus musculus Gene: Vax2
Summary
InnateDB Gene IDBG-161559.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vax2
Gene Name ventral anterior homeobox containing gene 2
Synonyms Dres93
Species Mus musculus
Ensembl Gene ENSMUSG00000034777
Encoded Proteins
IDBP-161561
ventral anterior homeobox containing gene 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116035:
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83711264-83738313
Strand Forward strand
Band C3
Transcripts
ENSMUST00000037807 ENSMUSP00000035976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007409 axonogenesis
GO:0009950 dorsal/ventral axis specification
GO:0016055 Wnt signaling pathway
GO:0030900 forebrain development
GO:0043010 camera-type eye development
GO:0048048 embryonic eye morphogenesis
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116035
View Gene Order
ENSBTAG00000010605
Not yet available
Cross-References
SwissProt Q9WTP9
TrEMBL Q14B19
UniProt Splice Variant
Entrez Gene 24113
UniGene Mm.307165
RefSeq NM_011912
OMIM
CCDS CCDS20282
HPRD
IMGT
MGI ID MGI:1346018
MGI Symbol Vax2
EMBL AB020498 AF028715 BC090635 BC116389 BC116390 CH466523 Y17792
GenPept AAF21632 AAH90635 AAI16390 AAI16391 BAA76867 CAB56169 EDK99098
RNA Seq Atlas 24113

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca