Mus musculus Gene: Vax2
Summary
InnateDB Gene IDBG-161559.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vax2
Gene Name ventral anterior homeobox containing gene 2
Synonyms Dres93;
Species Mus musculus
Ensembl Gene ENSMUSG00000034777
Encoded Proteins
ventral anterior homeobox containing gene 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116035:
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83711264-83738313
Strand Forward strand
Band C3
Transcripts
ENSMUST00000037807 ENSMUSP00000035976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007409 axonogenesis
GO:0009950 dorsal/ventral axis specification
GO:0016055 Wnt signaling pathway
GO:0030900 forebrain development
GO:0043010 camera-type eye development
GO:0048048 embryonic eye morphogenesis
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.307165
RefSeq NM_011912
OMIM
CCDS CCDS20282
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas