Homo sapiens Gene: VAX2
InnateDB Gene IDBG-55700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAX2
Gene Name ventral anterior homeobox 2
Synonyms DRES93
Species Homo sapiens
Ensembl Gene ENSG00000116035
Encoded Proteins
ventral anterior homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:70900590-70933446
Strand Forward strand
Band p13.3
ENST00000234392 ENSP00000234392
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0031490 chromatin DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0007398 ectoderm development
GO:0007409 axonogenesis
GO:0007601 visual perception
GO:0009950 dorsal/ventral axis specification
GO:0016055 Wnt signaling pathway
GO:0030900 forebrain development
GO:0043010 camera-type eye development
GO:0048048 embryonic eye morphogenesis
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q9UIW0
UniProt Splice Variant
Entrez Gene 25806
UniGene Hs.249170
RefSeq NM_012476
OMIM 604295
EMBL AB593145 BC006336 BT007035 CH471053 Y17791
GenPept AAH06336 AAP35683 BAJ84079 CAB56166 EAW99792
RNA Seq Atlas 25806