Version 5.4
Mus musculus Gene: Rusc1
Summary
InnateDB Gene IDBG-162487.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rusc1
Gene Name RUN and SH3 domain containing 1
Synonyms 2210403N08Rik; AA408288; NESCA
Species Mus musculus
Ensembl Gene ENSMUSG00000041263
Encoded Proteins
IDBP-162489
RUN and SH3 domain containing 1
IDBP-162491
RUN and SH3 domain containing 1
IDBP-620917
RUN and SH3 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 19365808
[Homo sapiens] RUSC1 binds to IKBKG and TRAF6, representing a molecular link between NGF signalling and IKK complex activity.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160753:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:89083981-89093363
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000052539 ENSMUSP00000056640
ENSMUST00000090929 ENSMUSP00000088447
ENSMUST00000166687 ENSMUSP00000130477
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0000209 protein polyubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0014069 postsynaptic density
GO:0015630 microtubule cytoskeleton
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030054 cell junction
GO:0031410 cytoplasmic vesicle
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000160753
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
mapktrkpathway
Trk receptor signaling mediated by the MAPK pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27687
RefSeq NM_001083807 NM_001083808 NM_028188 XM_006502134
OMIM
CCDS CCDS38485 CCDS38486 CCDS50956
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca