|Homo sapiens Gene: MNT|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||MNT, MAX dimerization protein|
|Synonyms||bHLHd3; MAD6; MXD6; ROX;|
MAX binding protein
MAX network transcriptional repressor
|Useful resources||Stemformatics EHFPI ImmGen|
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 17:2384060-2401118|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Possible paralog/unusual divergence/ gene prediction error
|UniProt Splice Variant|
|UniGene||Hs.619541 Hs.626579 Hs.632239|
|RNA Seq Atlas|